Last update
9/17/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Moderately Good
Based on 43 Reviews
7.6
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Magnesium (as magnesium oxide)
400 mg
95%
Top Medical Research Studies
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
Most Useful Reviews
9
Pain relief achieved
60 people found this helpful
Despite being cheap, this product worked wonders! After a month of magnesium from France, I felt much better. My left side pain, which the doctor advised to treat with magnesium, ceased. I shared this product with a friend, and we both feel well after taking it.
Read More
9
Cramps resolved
7 people found this helpful
Goodbye leg cramps and hello sound sleep! Many are unaware of magnesium deficiency and its symptoms, including muscle pain and leg cramps. I take this magnesium consistently, and I've noticed my sleep has improved and leg cramps have disappeared, with my menstruation also becoming less painful.
Read More
9
Pain-free periods
6 people found this helpful
This is my first experience with this product. After nearly three weeks of use, I noticed my period arrived without any pain, despite initially taking it for period pain! I highly recommend it to any girl who endures this issue.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
- All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 43 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain relief achieved
60 people found this helpful
Despite being cheap, this product worked wonders! After a month of magnesium from France, I felt much better. My left side pain, which the doctor advised to treat with magnesium, ceased. I shared this product with a friend, and we both feel well after taking it.
Read More
9
Cramps resolved
7 people found this helpful
Goodbye leg cramps and hello sound sleep! Many are unaware of magnesium deficiency and its symptoms, including muscle pain and leg cramps. I take this magnesium consistently, and I've noticed my sleep has improved and leg cramps have disappeared, with my menstruation also becoming less painful.
Read More
9
Pain-free periods
6 people found this helpful
This is my first experience with this product. After nearly three weeks of use, I noticed my period arrived without any pain, despite initially taking it for period pain! I highly recommend it to any girl who endures this issue.
Read More
9
Eliminated bone pain
3 people found this helpful
I had been tormented by severe cramps that made me cry out in pain. On my doctor’s advice, I started taking magnesium during my pregnancy, and I’ve recently realised that I haven't experienced any bone pain for a long time. The packaging is large and lasts quite a while. Highly recommend! Health to everyone!
Read More
9
Improved muscle pain
3 people found this helpful
We are purchasing this product for the second time, and I plan to continue using this magnesium and vitamin B. It helps me sleep well, feel energised, and alleviates muscle pain. The size is good, and there is no unpleasant taste. The quality is excellent, but please consult your doctor before use.
Read More
Frequently Asked Questions
9
Pain-free periods
6 people found this helpful
This is my first experience with this product. After nearly three weeks of use, I noticed my period arrived without any pain, despite initially taking it for period pain! I highly recommend it to any girl who endures this issue.
9
Eliminated bone pain
3 people found this helpful
I had been tormented by severe cramps that made me cry out in pain. On my doctor’s advice, I started taking magnesium during my pregnancy, and I’ve recently realised that I haven't experienced any bone pain for a long time. The packaging is large and lasts quite a while. Highly recommend! Health to everyone!
9
Eliminated back pain
1 people found this helpful
This is the best magnesium I've encountered. Since I started taking it, I've not needed medication for my back pain. Working in a factory, I have to rely on it, but it seems like magic; within a few days, the pain evaporates.
4
Temporary relief
3 people found this helpful
I observed little improvement after taking a month's course prescribed by my neurologist, though the muscle pain eased and convulsions ceased. However, after a month, all signs of discomfort, including bone pain, gradually returned, indicating the course duration was insufficient.
7.5
Reduced neck pain
4 people found this helpful
I felt a noticeable improvement within the first week, particularly a decline in my neck pain and back issues after taking just three pills a day.
9
Cramps resolved
7 people found this helpful
Goodbye leg cramps and hello sound sleep! Many are unaware of magnesium deficiency and its symptoms, including muscle pain and leg cramps. I take this magnesium consistently, and I've noticed my sleep has improved and leg cramps have disappeared, with my menstruation also becoming less painful.
9
Reduced menstrual pain
6 people found this helpful
Taking three capsules a day has significantly reduced my menstrual pain after three weeks; I no longer need painkillers.
9
Relieved bone pain
2 people found this helpful
I suffered from osteochondrosis, but since taking magnesium with vitamin B6, it has made a significant difference; my bone pain has subsided.
7.5
Strengthens bones
42 people found this helpful
This magnesium is of high quality and aids in strengthening muscles, joints, and bones through better calcium absorption. It's beneficial for the nervous system and promotes healthy sleep due to its vitamin B6 content. I’ve ordered a second package as the first one is almost finished. I highly recommend it!
7.5
Improved wellbeing
2 people found this helpful
I’ve been taking Solgar Magnesium with Vitamin B6 for several months now, and it has greatly improved my health. I used to suffer from leg cramps, headaches, and fatigue, but since starting this supplement, I feel calmer and more energetic. Magnesium is vital for muscle relaxation, nerve transmission, and bone formation.
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
References
- Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. 10.3389/fbioe.2023.1153969
- Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
- Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
